laboratory personnel

Zhigailov Andrey Viktorovich

Ph.D in biology

Head of the Laboratory of protein and nucleic acids

Phone: +7 (727) 239-05-07

E-mail: andrzhig@gmail.com

Andrey Zhigailov graduated from the biological faculty of al-Farabi Kazakh National University in 2002. He earned his master’s degree in biotechnology in 2004. He completed postgraduate studies at the Institute of molecular biology and biochemistry in 2006. He passed an internship at the Institute of chemical biology and fundamental medicine, Siberian branch of the Russian Academy of Sciences, Novosibirsk, Russia (2006); training on “Fundamentals of sequencing and fragmentary analysis” Warrington, UK (2007); internship on mastering the methods of working with miRNAs at the Institute of botany of Basel, Switzerland (2007). In 2018, he passed advanced training: “Methods and techniques for working with pathogens of especially dangerous infections of II-IV pathogenicity groups” 216 hours at the M. Aikimbaev Kazakh scientific center for quarantine and zoonotic infections in Almaty.

Since 2001 he had been working at the Laboratory of protein and nucleic acids of IMBB as: laboratory assistant – junior researcher – researcher – senior researcher. Between 2016 and 2022 – Leading researcher at the Laboratory of protein and nucleic acids of IMBB. Since January 2023, he has been appointed as a Head of the Laboratory. From 2012 to the present, he has been a scientific expert in reviewing and reviewing scientific projects and reports as part of a comprehensive review conducted by the National center for state scientific and technical expertise JSC.

He took part in 11 scientific projects and grants, in three of them he was a scientific supervisor. Hirsch index: 3, Researcher ID (Web of Science): N-6073-2015, Scopus ID: 6508121286. ORCID: https://orcid.org/0000-0002-9646-033X.

In 2016, he was awarded the “Algys” gratitude of the Ministry of Education and Science of the Republic of Kazakhstan.

Iskakov Bulat Kudaibergenovich

Doctor of biological sciences, Professor

Leading researcher


E-mail: bulat.iskakov@mail.ru, kryldakov@mail.ru

 

Iskakov Bulat Kudaibergenovich was born on September 14, 1951 in Alma-Ata city.

He graduated from the biology faculty of C.M. Kirov Kazakh State University in 1973, in the same year he entered full-time graduate school of the Institute of botany of the Academy of Sciences of the Kazakh SSR in the laboratory of biochemistry of protein and nucleic acids. In 1981, under the guidance of Murat Aitkhozhin he defended his candidate thesis on the topic “Polypeptide composition of various classes of informosomes and RNA-binding proteins of higher plant cells” in the Dissertation council at the Institute of botany. In 1997 Bulat Iskakov defended his doctoral dissertation on the topic “Study of molecular mechanisms and regulation of protein biosynthesis in plants” in the Dissertation council at the M. V. Lomonosov Moscow State University. In 1999 he passed the nostrification and was awarded the degree of Doctor of biological sciences. In 2002 Bulat Iskakov awarded the title of professor in the “biology” specialty.

He completed internships in many scientific centers: Russian Federation (Moscow, Pushchino); Great Britain (Canterbury, Dundee); Switzerland (Basel); Israel (Volkani Center).

Under the leadership of Bulat Iskakov for the first time in Kazakhstan established and improved biotechnology to obtain drought-resistant transgenic plants (potatoes, tobacco), as well as plants resistant to phytopathogenic viruses, using approaches antisense RNA and RNA interference. For the first time it was established that specific mechanisms of translational control, different from animals can function in plant cells, which can provide the initiation of translation without the participation of some protein factors.

From 1994 to 2004 Bulat Iskakov led research projects in the framework of many international projects financed by grants from foreign funds INTAS, US AID, INCO COPERNICUS, Royal Society, SCOPES. These projects have been successfully implemented together with scientists from Switzerland, Germany, Great Britain, Russia and Israel.

His fundamental research of molecular mechanisms of transmission regulation in plants in normal and under the influence of adverse environmental factors is a priority and meets the requirements of the international standard. This is proved by publications in international scientific journals: FEBS Letters; Biochimica et Biophysica Acta; European Journal of Biochemistry; Biochimie; Plant Science; Nuclear Acids Research; Molecular biology; Biochemistry; plant Physiology; Biopolymers and cell. At many international conferences Bulat Iskakov invited as a guest speaker. He has an h-index of 6, published more than 200 articles in international journals, conferences and symposia. His publications received more than 128 citations.

He has developed a “Gene Engineering” course of study and from 1998 to the present time has been teaching students at al-Farabi Kazakh State University. Under the guidance of Bulat Iskakov there were completed and defended 6 candidates, 1 doctoral and 1 PhD dissertations.

Bulat Iskakov was a member of the editorial boards of several scientific journals, a member of the National Scientific Councils in the priority areas of “Life and Health Sciences” (2015-2017), “Research in the field of natural sciences” (2020-2022).

In 1979 he was awarded the title of laureate of the Lenin Komsomol Prize of the USSR in the field of science and technology as part of a group of scientists; In 2019 he received the badge of the Ministry of Education and Science of the Republic of Kazakhstan “Gylymdy damytuga sinirgen enbegi ushin”.

Karpova Oksana Vladislavovna

PhD in biology

Leading researcher

E-mail: o.karpova@imbb.org.com, oxkarpova@mail.ru

Oksana Karpova graduated from the Zhdanov State University (Irkutsk, Russian Federation) with a degree in physiology in 1989. From 1989 to 1990 she completed an internship at the Department of physical and chemical biology of the Zhdanov State University. In 2005, she defended her PhD thesis on the topic “Study of the regulatory regions of the genomic RNA of the potato Y-virus as molecular targets for antisense RNAs in order to create resistant transgenic plants.”

She completed internships at the Institute of field and horticultural cultures in Volkani – Center, Israel (1995), at the Agricultural biotechnology center in Gedolle, Hungary (2000).

From 1990 to 2008 she had been working at the M. Aitkhozhin Institute of molecular biology and biochemistry as: senior laboratory assistant – junior researcher – researcher. Since 2008 to the present she is a Leading Researcher at the Laboratory of protein and nucleic acids of IMBB.

She took part at five projects as the principal executor. She was the project Manager of the grant on the topic: “Identification of S proteins of the potato virus, which suppress the process of RNA interference of host cells, in order to study the molecular mechanisms of the interaction between the virus and the plant and the recovery of viral material” (a new method for the recovery of potato plants has been developed) from 2018 to 2020. She is a co-author of 4 innovative patents of the Republic of Kazakhstan.

Research interests: Molecular biology of viruses, RNA interference in plants. Obtaining genetically modified plants with resistance to biotic and abiotic stresses. Creation of transgenic plants of tobacco, potato, rapeseed.

Polimbetova Naila Seitzhanovna

PhD in Biology

Leading researcher

Naila Polimbetova graduated from the biological faculty of al-Farabi Kazakh National University in 1973. She completed postgraduate studies at the laboratory of biochemistry of protein and nucleic acids at the Institute of botany of the Academy of Sciences of the Kazakh SSR (1976). In 1985 she defended her thesis on the topic: “Nuclear ribonucleoproteins of cells of higher plants” in the dissertation council at the Institute of molecular biology and biochemistry of the Academy of Sciences of the Kazakh SSR under the guidance of Academician Murat Abenovich Aitkhozhin.

Naila Polimbetova completed internships with advanced training at scientific centers in Russian Federation (Moscow State University, Pushchino), Gustave Roussy Institute of Oncology (Paris, France).

Between 1973 and 1983 she worked at the Institute of botany of the Academy of Sciences of the Kazakh SSR in the Laboratory of biochemistry of protein and nucleic acids in the direction: molecular biology and biochemistry of plants as: a senior laboratory assistant – junior researcher. From 1983 to 2005 she worked at the Institute of molecular biology and biochemistry in the Laboratory of cell engineering as a junior researcher – researcher – senior researcher. Since 2005 to the present – she is a Leading researcher at the Laboratory of protein and nucleic acids at the IMBB.

Naila Polimbetova is an author of more than 100 publications, including 13 articles in top international peer-reviewed scientific journals (FEBS Letters; Biochemistry; Plant Science; Nucleic Acids Research, Biochemistry, Bioorganic Chemistry, Molecular Biology) and abstracts of reports in collections of international conferences. She is a co-author of 5 innovative patents of the Republic of Kazakhstan. She has Hirsch index – 3, more than 54 citations, 13 publications in Scopus.

Over the years of work, she participated in scientific research within the framework of many international grants from various foundations (USAID, INTAS, COPERNICUS, SCOPES). N. Polimbetova was a member of the dissertation council for the defense of dissertations at the M. Aitkhozhin Institute of molecular biology and biochemistry, specializing in biochemistry and served as scientific secretary of the dissertation council.

In 2016 Naila Polimbetova was awarded a diploma of the Committee of science of the Ministry of Education and Science of the Republic of Kazakhstan for the implementation of priority fundamental research on the molecular mechanisms of regulation of protein synthesis in plant cells, as well as applied research on the development of new biotechnologies for plant adaptation to environmental stress.

Stanbekova Gulshan Esenbekovna

PhD in Biology

Leading researcher

Gulshan Stanbekova graduated from the biology faculty of M.V. Lomonosov Moscow State University in 1986, studied full-time postgraduate degree at the Department of genetics, Faculty of biology, M.V. Lomonosov Moscow State University. In 1992 she defended her Ph.D. thesis in “genetics” specialty at the N.I. Vavilov Institute of general genetics (Moscow).

She completed internships in leading foreign centers: the Institute Gustav Rossi (France), Darmstadt Technical University (Germany), Volkani Center (Israel). She specializes in the following areas: study of photosynthesis genes, heterologous expression of recombinant proteins, construction of gene libraries, obtaining transgenic and transplastomic plants producing target proteins.

She was the grant project manager of AP05132066 “Development of technology for the expression of recombinant sheep pox virus antigens in transplastomic plants” (2018-2020). She is an author of 44 publications, has h-index – 4, more than 153 citations in the Web of Science database.

Alexandrova Alena Mikhailovna

Master in biotechnology

Researcher

E-mail: alena_pisarenko@inbox.ru, alyona.alexandrova1987@gmail.com

Alena Alexandrova graduated from the biology faculty of al-Farabi Kazakh National University in 2009. She received her Master’s degree in biotechnology in 2011. Since 2017, she is a PhD candidate at al-Farabi Kazakh National University.

In 2019, she completed a 3-month internship under the doctoral program at CIRAD-INRA-SupAgro in the “Biology and Genetics of Plant-Pathogen Interactions” research group (Montpellier, France).

Since 2009 to 2021 she had been working at the Laboratory of protein and nucleic acids of IMBB as a laboratory assistant – junior researcher. From 2021 to the present, she is a researcher at the Laboratory of protein and nucleic acids of IMBB.

H-index: 2 (Scopus), Scopus author ID: 57195066389, Researcher ID: Q-1176-2017, ORCID, 0000-0002-6501-3510.

Nargilova Rufina Mustafaevna

Master in biotechnology

Junior researcher

Rufina Nargilova graduated from the biology faculty of al-Farabi Kazakh National University. She has a Master’s Degree in biotechnology.

In 2010, she started working as a laboratory assistant at the Laboratory of protein and nucleic acids of M.A. Aitkhozhin Institute of molecular biology and biochemistry. From 2014 to the present she is a junior researcher at the Laboratory of protein and nucleic acids of IMBB.

In 2013 and 2014 she completed an internship at the All-Russian research institute of agricultural biotechnology in Moscow, where she learned the modern method for assessing gene expression in real-time PCR. She is an author of more than 15 publications, co-author of 3 innovative patents of the Republic of Kazakhstan.

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